DSIP (Delta Sleep-Inducing Peptide) is a nonapeptide first isolated from rabbit cerebral venous blood, studied for its influence on delta-wave EEG activity, circadian signaling, and stress-axis regulation. Supplied as a ≥99% HPLC-verified lyophilized powder for laboratory research use only.
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Third-Party Tested by Janoshik Analytical
Compound Information
Technical specifications
Lyophilized powder; keep sealed, dry, and protected from light
Store at a stable temperature; minimize warming/cooling cycles
Aliquot after reconstitution; avoid repeated freeze–thaw cycles
Lyophilized Powder
-20°C preferred; 2–8°C for short-term handling
Reconstituted
2–8°C
DSIP (Delta Sleep-Inducing Peptide) is a nine-residue neuromodulatory peptide first isolated from the cerebral venous blood of rabbits during induced slow-wave sleep, from which it takes its name. It is studied for its reported association with delta-wave EEG activity, though its precise receptor target remains uncharacterized — a fact that makes it an ongoing subject of mechanistic investigation rather than a settled tool compound. Beyond sleep architecture, DSIP is examined in the context of circadian signaling, hypothalamic–pituitary–adrenal axis regulation, and stress response models. Supplied as a high-purity lyophilized powder for reproducible in-vitro and approved in-vivo work. This product is for laboratory research and development purposes only and must be handled by qualified professionals. Not for human, therapeutic, or diagnostic use.
Delta-Wave EEG Activity
Originally identified through its association with slow-wave sleep, making it a reference peptide in EEG and sleep-architecture studies.
Circadian Signaling
Investigated for its role in rhythm entrainment and its interaction with melatonin and other circadian mediators.
HPA Axis Regulation
Studied for its influence on corticotropin signaling and stress-response pathways in preclinical models.
Uncharacterized Receptor Target
Its binding target remains unidentified, making DSIP an active subject of mechanistic and receptor-deorphanization research.
Compact, Stable Sequence
Its nine-residue length makes it straightforward to dissolve, dose, and handle consistently across experimental replicates.
≥99% HPLC Purity
Every batch is HPLC-verified and supplied lyophilized, ensuring reproducible results across long study timelines.
DSIP is a nine-residue neuromodulatory peptide originally isolated from the cerebral venous blood of rabbits during slow-wave sleep, from which its name derives.
Its receptor target has not been identified. This is a genuine open question in the literature, and it is part of why DSIP remains a subject of active mechanistic investigation rather than a well-characterized tool compound.
It appears in studies of sleep architecture and delta-wave EEG activity, circadian rhythm signaling, and hypothalamic–pituitary–adrenal axis regulation in stress-response models.
No. This product has not been evaluated by the FDA and is strictly intended for research and development purposes by qualified professionals only.