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SS-31 50mg

SS-31 50mg

SS-31 (Elamipretide) is a mitochondria-targeting tetrapeptide studied for its selective binding to cardiolipin in the inner mitochondrial membrane, supporting research into cristae structure, electron transport efficiency, and oxidative stress. Supplied as a ≥99% HPLC-verified lyophilized powder for laboratory research use only.

+99% Purity Third-Party Tested COA Available

 139.99

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Compound Information

Technical specifications


Molecular Profile

What Is SS-31?

TypeMitochondria-Targeting Tetrapeptide
CAS Number736992-21-5
Molecular Weight639.79 g/mol
SynonymsElamipretide / MTP-131 / Bendavia
Amino Acids4 AA (Alternating cationic/aromatic motif)
SequenceD-Arg-Dmt-Lys-Phe-NH2
FormulaC32H49N9O5

Storage Requirements

Stability Information

Lyophilized powder; keep sealed, dry, and protected from light
Store at a stable temperature; minimize warming/cooling cycles
Aliquot after reconstitution; avoid repeated freeze–thaw cycles

Lyophilized Powder

-20°C preferred; 2–8°C for short-term handling

Reconstituted

2–8°C


About SS-31

SS-31 (Elamipretide) is a synthetic tetrapeptide designed with an alternating cationic–aromatic motif that allows it to accumulate in the inner mitochondrial membrane independently of membrane potential. It is widely researched for its selective association with cardiolipin, the signature phospholipid of the inner membrane, and the downstream effects this has on cristae architecture and electron transport chain efficiency. As a result, SS-31 serves as a reference compound in studies of mitochondrial bioenergetics, oxidative stress, and age-related mitochondrial decline. Supplied as a high-purity lyophilized powder for reproducible in-vitro and approved in-vivo work. This product is for laboratory research and development purposes only and must be handled by qualified professionals. Not for human, therapeutic, or diagnostic use.


Research Highlights

Cardiolipin Binding

Selectively associates with cardiolipin in the inner mitochondrial membrane — a targeted tool for probing membrane-lipid interactions.

Electron Transport Efficiency

Investigated for its effect on respiratory-chain supercomplex organization and ATP-generating capacity in isolated mitochondria.

Oxidative Stress Models

Used as a reference peptide in studies of reactive oxygen species generation and mitochondrial redox balance.

Potential-Independent Uptake

Accumulates in the inner membrane without depending on membrane potential, unlike conventional cationic mitochondrial probes.

Cristae Structure Research

Studied for its influence on cristae curvature and membrane organization in models of age-related mitochondrial decline.

≥99% HPLC Purity

Every batch is HPLC-verified and supplied lyophilized, ensuring reproducible results across long study timelines.

Product Specifications

Molecular Formula
C32H49N9O5
Molecular Weight
639.79 g/mol
CAS Number
736992-21-5
Sequence
D-Arg-Dmt-Lys-Phe-NH2
Purity
≥99% (HPLC verified)
Form
Lyophilized powder
Appearance
White to off-white powder
Solubility
Soluble in water, bacteriostatic water
Storage
-20°C (lyophilized), 2–8°C (reconstituted)

Research Studies

Frequently Asked Questions

What is SS-31?

SS-31, also known as Elamipretide, is a synthetic tetrapeptide researched for its selective accumulation in the inner mitochondrial membrane and its binding to cardiolipin.

Why is SS-31 used in mitochondrial research?

Its cardiolipin affinity makes it a targeted reference compound for investigating cristae architecture, electron transport chain organization, and oxidative stress in isolated mitochondria and cell models.

How does it differ from other mitochondrial probes?

Unlike conventional cationic probes that depend on membrane potential to accumulate, SS-31 concentrates in the inner membrane through lipid association — useful in models where potential is compromised.

Is this product approved for human use?

No. This product has not been evaluated by the FDA and is strictly intended for research and development purposes by qualified professionals only.

SS-31 molecular structure

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