NAD+ (Nicotinamide Adenine Dinucleotide) is an essential redox coenzyme central to cellular energy metabolism and a required substrate for sirtuins and PARP enzymes. Supplied as a ≥99% HPLC-verified lyophilized powder for laboratory research use only.
€ 64.99
23 in stock
Third-Party Tested by Janoshik Analytical
Compound Information
Technical specifications
Lyophilized powder; keep sealed, dry, and protected from light
Hygroscopic — minimize air exposure when weighing
Unstable in alkaline solution — prepare working stocks fresh
Lyophilized Powder
-20°C preferred; 2–8°C for short-term handling
Reconstituted
2–8°C; use promptly, avoid alkaline buffers
NAD+ (Nicotinamide Adenine Dinucleotide) is a dinucleotide coenzyme present in every living cell, and one of the most fundamental molecules in metabolism. It serves two distinct roles. As a redox carrier, it cycles between its oxidized (NAD+) and reduced (NADH) forms to shuttle electrons through glycolysis, the citric acid cycle, and oxidative phosphorylation. Separately — and this is where most current research interest sits — it acts as a consumed substrate for enzymes including the sirtuins (SIRT1–7) and PARPs, which cleave NAD+ rather than merely borrowing its electrons. That consumption links cellular NAD+ availability directly to deacetylation, DNA repair, and gene regulation. Supplied as a high-purity lyophilized powder for reproducible in-vitro work. This product is for laboratory research and development purposes only and must be handled by qualified professionals. Not for human, therapeutic, or diagnostic use.
Central Redox Carrier
Cycles between NAD+ and NADH to shuttle electrons through glycolysis, the citric acid cycle, and oxidative phosphorylation.
Sirtuin Substrate
Required as a consumed substrate by SIRT1–7, linking cellular NAD+ levels directly to deacetylation and gene regulation.
PARP & DNA Repair
PARP enzymes consume NAD+ during DNA damage response, making its availability a limiting factor in repair studies.
Mitochondrial Bioenergetics
The NAD+/NADH ratio is a core readout of cellular redox state in mitochondrial function assays.
Enzymatic Assay Reagent
A standard cofactor in dehydrogenase assays, where NADH formation is tracked spectrophotometrically at 340nm.
≥99% HPLC Purity
Every batch is HPLC-verified and supplied lyophilized, ensuring reproducible results across long study timelines.
