KPV is the C-terminal tripeptide fragment of α-MSH (Lys-Pro-Val), studied for its anti-inflammatory signaling activity without the pigmentary effects of the parent hormone. Supplied as a ≥99% HPLC-verified lyophilized powder for laboratory research use only.
€ 39.99
98 in stock
Third-Party Tested by Janoshik Analytical
Compound Information
Technical specifications
Lyophilized powder; keep sealed, dry, and protected from light
Store at a stable temperature; minimize warming/cooling cycles
Aliquot after reconstitution; avoid repeated freeze–thaw cycles
Lyophilized Powder
-20°C preferred; 2–8°C for short-term handling
Reconstituted
2–8°C
KPV is the C-terminal tripeptide fragment (Lys-Pro-Val) of alpha-melanocyte-stimulating hormone (α-MSH). It retains much of the parent hormone’s anti-inflammatory signaling activity while lacking the melanocortin receptor engagement responsible for pigmentary effects, making it a cleaner tool for isolating inflammatory pathways. KPV is widely researched for its influence on NF-κB signaling, pro-inflammatory cytokine expression, and epithelial barrier function, particularly in gut and skin models. Its small size and stability make it a practical reference compound for in-vitro assays. Supplied as a high-purity lyophilized powder for laboratory research and development purposes only. Must be handled by qualified professionals. Not for human, therapeutic, or diagnostic use.
Anti-Inflammatory Signaling
Retains the inflammatory-modulating activity of the parent α-MSH hormone in a compact three-residue format.
NF-κB Pathway Studies
Investigated for its effect on NF-κB nuclear translocation and downstream pro-inflammatory gene expression.
Epithelial Barrier Function
A common reference compound in gut and skin models examining tight-junction integrity and mucosal signaling.
Cytokine Expression
Studied for its modulation of pro-inflammatory cytokine output in stimulated cell culture models.
Clean Pathway Isolation
Lacks the pigmentary receptor activity of full-length α-MSH, allowing inflammatory effects to be studied in isolation.
≥99% HPLC Purity
Every batch is HPLC-verified and supplied lyophilized, ensuring reproducible results across long study timelines.
