LL-37 is the C-terminal fragment of human cathelicidin (hCAP18), a 37-residue cationic peptide studied for its role in innate immune signaling, antimicrobial activity, and wound-repair pathways. Supplied as a ≥98% HPLC-verified lyophilized powder for laboratory research use only.
€ 39.99
30 in stock
Third-Party Tested by Janoshik Analytical
Compound Information
Technical specifications
Lyophilized powder; keep sealed, dry, and protected from light
Highly cationic — minimize contact with untreated glass surfaces
Aliquot after reconstitution; avoid repeated freeze–thaw cycles
Lyophilized Powder
-20°C preferred; 2–8°C for short-term handling
Reconstituted
2–8°C
LL-37 is the 37-residue C-terminal fragment of human cathelicidin (hCAP18), the only cathelicidin-derived antimicrobial peptide identified in humans. Its amphipathic α-helical structure and strong net positive charge allow it to associate with anionic microbial membranes, making it a widely used reference peptide in innate immunity research. Beyond direct antimicrobial activity, LL-37 is investigated for its immunomodulatory role — including chemotaxis, cytokine signaling, angiogenesis, and epithelial wound repair. Supplied as a high-purity lyophilized powder for reproducible in-vitro and approved in-vivo work. This product is for laboratory research and development purposes only and must be handled by qualified professionals. Not for human, therapeutic, or diagnostic use.
Innate Immune Signaling
The only human cathelicidin peptide — a core reference compound for studying host-defense mechanisms at epithelial barriers.
Membrane Interaction Studies
Its cationic, amphipathic helix makes it a standard model for investigating peptide–lipid bilayer association and disruption.
Chemotaxis & Cytokine Response
Investigated for its immunomodulatory role in recruiting immune cells and shaping downstream inflammatory signaling.
Wound Repair & Angiogenesis
Studied for its influence on keratinocyte migration, re-epithelialization, and endothelial signaling in tissue-repair models.
Antimicrobial Reference Peptide
Frequently used as a benchmark control in comparative assays of novel antimicrobial peptide candidates.
≥98% HPLC Purity
Every batch is HPLC-verified and supplied lyophilized, ensuring reproducible results across long study timelines.
