Ipamorelin is a pentapeptide growth hormone secretagogue and selective ghrelin receptor (GHS-R1a) agonist, studied for its highly specific stimulation of growth hormone release without measurable effect on cortisol or prolactin. Supplied as a ≥99% HPLC-verified lyophilized powder for laboratory research use only.
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Third-Party Tested by Janoshik Analytical
Compound Information
Technical specifications
Lyophilized powder; keep sealed, dry, and protected from light
Store at a stable temperature; minimize warming/cooling cycles
Aliquot after reconstitution; avoid repeated freeze–thaw cycles
Lyophilized Powder
-20°C preferred; 2–8°C for short-term handling
Reconstituted
2–8°C
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that acts as a selective agonist at the ghrelin receptor (GHS-R1a) in the pituitary. What distinguishes it from earlier secretagogues such as GHRP-6 and GHRP-2 is its selectivity: in the studies that established its profile, it triggered growth hormone release without the accompanying rise in cortisol, prolactin, or ACTH seen with less selective compounds, and without the appetite stimulation associated with strong ghrelin agonism. That clean signal is why it remains a standard reference compound in GH-axis research — investigators can attribute observed downstream effects to GH itself rather than to confounding hormonal noise. It is frequently paired with a GHRH analog such as CJC-1295 No-DAC in study designs exploring synergistic pituitary stimulation, since the two act through complementary receptor pathways. Supplied as a high-purity lyophilized powder for reproducible in-vitro and approved in-vivo work. This product is for laboratory research and development purposes only and must be handled by qualified professionals. Not for human, therapeutic, or diagnostic use.
Receptor Selectivity
A selective GHS-R1a agonist — stimulating GH release without the cortisol, prolactin, or ACTH elevation seen with earlier GHRPs.
Clean Signal Profile
Minimal off-target hormonal activity lets researchers attribute downstream effects to GH itself rather than confounding variables.
Complementary Pathway
Acts through the ghrelin receptor rather than the GHRH receptor — commonly paired with GHRH analogs in synergy studies.
Compact Pentapeptide
Just five residues with a C-terminal amide — a short, stable structure that is straightforward to synthesize and characterize.
GH–IGF-1 Axis Studies
A reference secretagogue for investigating pituitary response and downstream IGF-1 signaling in controlled study models.
≥99% HPLC Purity
Every batch is HPLC-verified and supplied lyophilized, ensuring reproducible results across long study timelines.
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that acts as a selective agonist at the ghrelin receptor (GHS-R1a), stimulating growth hormone release from the pituitary.
Its defining feature is selectivity. Where earlier GHRPs also elevate cortisol, prolactin, and ACTH, Ipamorelin was characterized as producing GH release without those off-target hormonal responses.
Ipamorelin acts at the ghrelin receptor while GHRH analogs such as CJC-1295 No-DAC act at the GHRH receptor. Because the pathways are complementary, the pairing is a common design in studies investigating synergistic pituitary stimulation.
No. This product has not been evaluated by the FDA and is strictly intended for research and development purposes by qualified professionals only.
